Analysis of the Primary and Post-Treatment Antibiotic Resistance of Helicobacter pylori in the Nanjing Area

Background: Resistance of Helicobacter pylori?H. pylori? to antibiotics is increasing worldwide. In order understand the current situation antibiotic resistance in Nanjing and provide a reasonable basis for clinical selection cure H. Pylori. Objective: To investigate status Pylori area, analyze primary post-treatment pylori this area. Methods: During period from July 2017 December 2019, 1533 gastric mucosal specimens patients with positive confirmed by breath test or rapid urease were collected isolation identify pylori. The agar dilution method was used test. Results: result showed that rates amoxicillin, clarithromycin, levofloxacin, furazolidone, tetracycline metronidazole 2.74%, 47.03%, 33.59%, 0.91%, 0.52% 80.76%, respectively 2019. (primary Vs post-treatment) 1.83% 6.08%, 38.62% 77.81%, 27.41% 56.23%, 0.58% 2.13%, 0.33% 1.22%, 78.57% 88.75%, respectively. Conclusions: Antibiotic remained problem effective eradication pathogen its associated diseases For patients, clinicians should took into account regional rate, personal exposure history, economic benefit ratio, adverse reactions, availability other aspects?